Anastrozole

Anastrazole(CAS Number:120511-73-1)

Anastrazole, an aromatize inhibitor is used for the treatment of  advanced breast cancer in postmenopausal women those who have failed to respond to therapy with other drugs, such as tamoxifen. It works by decreasing the amount of estrogen synthesised in the body and it helps the tumors to shrink and slow down their growth. It is contraindicated in pregnancy and lactation. Trouble sleeping, tiredness, headache, vomiting, dizziness are the side effects of this medication. It is to be avoided during the intake of medicines such as tamoxifen, oestrogens  because of the serious interactions that may occur.  
Chemical formula:  C₁₇H₁₉N₅      
Synonyms:10-Methoxy-5H-dibenz[b,f]azepine-5-carbonylchloride;1,3-   Benzenediacetonitrile,a,a,a',a'-tetramethyl-5-(1H-1,2,4-triazol-1-ylmethyl)-(9CI);2,2'-[5-(1H-1,2,4-triazol-1-ylmethyl)-1,3-phenylene]di(2-methylpropionitrile);2-[3-(2-Cyano-2-propyl)-5-(1,2,4-triazol-1-ylmethyl)phenyl]-2-methylpropiononitrile;Asiolex;Anastrol;Tetramethyl-5-(1H-1,2,4-triazol-1ylmethyl) 1,3-benzenediacetionitrile;
Molecular weight:293.37
Melting Point:     81-82°C
Assay : 98-102 %
Boiling Point: 469.718°C at 760 mmHg
Flash Point:   237.877°C
Appearance: white to off-white crystalline powder
Packaging:10/100g/Aluminium foiled bags