Busulfan

Product Description

Busulfan :

Busulfan is a highly lipophilic molecule that easily crosses the blood brain barrier. It has been used in the treatment of chronic myeloid leukemia. They stop the tumor growth by cross-linking guanine bases in DNA double-helix strands and directly attacking DNA. Higher busulfan exposure due to concomitant treatment of Itraconazole could lead to toxic plasma levels in some patients. This medication should be cautiously used in patients whose bone marrow may have been compromised by prior irradiation or chemotherapy, or whose marrow function is recovering from previous cytotoxic therapy.
Chemical formula: C6H14O6S2
Synonyms:1,4-Butanediol,dimethanesulfonate (8CI,9CI); Methanesulfonic acid, tetramethylene ester (6CI); 1,4-Butanedioldimesylate; Busilvex; Busulphan; Citosulfan; 2041;GT41; Glyzophrol; Leucosulfan; Mielevcin; Mielucin; Mileran; Misulban; Myeloleukon; Mylecytan; Sulfabutin; Tetramethylene bis[methanesulfonate
Molecular weight: 246.32
Melting Point: 114-118°C
Assay : 99 %
Boiling Point: 464°C at 760 mmHg
Flash Point: 234.4°C
Appearance: white crystalline solid
Package: 5/10/25kg/drum