Doxazosin mesylate

Doxazosin mesylate
Synonyms : Methanone,[4-(4-amino-6,7-dimethoxy-2-quinazolinyl)-1-piperazinyl](2,3-dihydro-1,4-benzodioxin-2-yl)-,methanesulfonate (1:1)

CAS No.:   77883-43-3

Formula:  C24H29N5O8S

Molecular Weight:   547.58

Melting Point:  275-277 C

Boiling Point:   718 C at 760 mmHg

Flash Point:   388 C

Appearance:   White crystalline powder

Specifications

Purity  : 99%

Appearance  : white crystalline powder

Storage:  Store at 4 C

Form:   Solid

Solubility:   Solubility: Slightly soluble in water.

Melting Point:   275-277C

Boling Point:  718C

Flash Point:  388C

Density:  1.371 g/cm3

Description

Doxazosin Mesylate is an alpha-blocker drug related to prazosin, specifically acting as an alpha-1-adrenoceptor antagonist. Doxazosin Mesylate inhibits the binding of norepinephrine to the alpha-1 receptors on the membrane of vascular smooth muscle cells. The primary effect of this inhibition is relaxed vascular smooth muscle tone (vasodilation), which decreases peripheral vascular resistance, leading to decreased blood pressure.